Basics
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Mechanical ventilation = machine delivers breaths (positive pressure ventilation, PPV).
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Normal breathing = negative pressure (diaphragm pulls air in).
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PPV dangers:
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Barotrauma (lung damage from overinflation).
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Can cause pneumothorax (popped lung).
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Suctioning (most tested NCLEX topic)
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Suction OUT only – never on insertion.
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<10 seconds per pass.
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Pre-oxygenate 100% O₂ for 30 seconds before suction.
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Avoid suctioning before ABGs – wait ≥20 min.
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Never suction routinely – only when needed (risk of trauma).
Key terms: acute lung injury, assess before intervention.
Oral Care & VAP (Ventilator-Associated Pneumonia)
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Prevention measures:
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Reposition q2h.
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Oral care with chlorhexidine q2h.
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Best indicators of VAP: sputum culture (+), fever >100.3°F, new infiltrates on CXR.
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Prevention protocols:
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Daily sedation vacations & weaning trials.
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HOB ≥30–45°.
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Oral care.
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Strict hand hygiene.
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NG Tube & Stress Ulcers
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No bolus feedings → aspiration risk. Use continuous feedings.
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Stress ulcers (from gastric secretions). Prevent with PPIs or H₂ blockers.
Complications
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Dropping O₂ sat → always assess first.
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Auscultate lungs, check for mucus plugs/secretions → suction.
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If unresolved → manual ventilation (ambu bag).
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Pneumothorax: from high PEEP/barotrauma.
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Hypotension: PPV compresses thoracic vessels → ↓ cardiac output.
Extubation
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Risks: airway obstruction, respiratory distress.
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Post-extubation care:
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Humidified O₂ mask.
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Oral care with sponges (no ice chips).
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NPO initially.
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High Fowler’s.
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Watch for:
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Atelectasis → encourage IS, turn/cough/deep breathe.
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Stridor (squeak) = airway emergency → report immediately.
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Tracheostomy Care
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New trach (<7 days): check tie tightness (1 finger under tie). Priority = maintain airway.
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If dislodged:
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Mature trach (>7 days) → reinsert with obturator/hemostat.
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New trach (<7 days) → cover with sterile occlusive dressing + bag-mask ventilation.
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Ventilator Alarms
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Low pressure alarm (low tidal volume) = disconnection, cuff leak, tube displacement.
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High pressure alarm (high blockage) = secretions, kinked tube, biting tube, coughing, pulmonary edema, pneumothorax.
Ventilator Modes
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AC (Assist Control) = full machine control (life support, post-CPR).
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SIMV (Synchronized Intermittent Mandatory Ventilation) = weaning mode, pt initiates some breaths.
Ventilator Settings
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VT (tidal volume): 500–800 mL (air per breath).
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RR (respiratory rate): 12–20/min.
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FiO₂: 35–100% (“feed me O₂”).
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PEEP: keeps alveoli open; watch for barotrauma/pneumothorax.
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PS (pressure support): helps spontaneous breaths.
Monitoring
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VE (minute ventilation) = air delivered per minute.
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PIP (peak inspiratory pressure) = max pressure during inspiration.
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Plateau pressure (Pplat) = measures lung compliance (↑ in ARDS/stiff lungs).
Key NCLEX Traps
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Always assess before intervening.
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Priority is airway, not infection prevention/dressing changes.
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High PEEP → barotrauma/pneumothorax.
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Stridor after extubation = emergency.
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No bolus feeds in intubated patients.
Mechanical Ventilation – Ventilator Settings & Initial Setup
Definition
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Ventilator settings = controls on a ventilator that determine how much ventilation (removing CO₂) and oxygenation (O₂ delivery) a patient receives.
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Adjusting settings = more or less support depending on patient need.
Core Ventilator Settings
1. Ventilator Modes
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Defines how the ventilator assists with inspiration (full vs partial support).
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Common modes:
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Assist Control (AC) → full support.
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SIMV → partial support, weaning.
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Pressure Support Ventilation (PSV) → assists spontaneous breaths.
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CPAP → continuous positive airway pressure.
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Other advanced modes: Volume Support, Control Mode Ventilation (CMV), APRV, MMV, IRV, HFOV.
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2. Tidal Volume (VT)
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Amount of air delivered per breath.
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Normal breathing: air inhaled/exhaled each cycle.
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Volume-controlled mode: set VT directly.
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Pressure-controlled mode: VT depends on pressure applied.
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Initial setting: 5–10 mL/kg IBW (commonly 6–8 mL/kg).
3. Respiratory Rate (Frequency, f)
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of breaths delivered per minute.
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Normal range: 10–20/min.
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Sets overall minute ventilation when combined with VT.
4. FiO₂ (Fraction of Inspired Oxygen)
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% O₂ delivered (21% = room air).
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Initial setting: 30–60%, unless patient was already on higher O₂.
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Severe hypoxemia: may start at 100%, but must wean to <60% ASAP (to avoid oxygen toxicity).
5. Inspiratory Flow Rate
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Speed of gas delivery.
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Normal: 40–60 L/min (up to 120 L/min if needed).
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If too low → ventilator dyssynchrony, ↑ work of breathing.
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If too high → ↓ mean airway pressure.
6. I:E Ratio (Inspiratory:Expiratory)
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Normal: 1:2 to 1:4.
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Longer expiratory times needed in obstructive disease (prevent air trapping).
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Adjusted by: flow rate, inspiratory/expiratory time, VT, and frequency.
7. Sensitivity (Trigger)
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Determines how much negative pressure patient must generate to trigger a breath.
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Normal: –1 to –2 cmH₂O.
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If too high → auto-triggering (extra breaths).
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If too low → patient struggles to trigger breaths.
8. PEEP (Positive End-Expiratory Pressure)
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Positive pressure left in lungs at end of expiration.
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Prevents alveolar collapse → improves oxygenation.
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Common use: refractory hypoxemia unresponsive to FiO₂.
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Initial: 4–6 cmH₂O.
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Caution: excessive PEEP → barotrauma, hypotension, pneumothorax.
9. Ventilator Alarms
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High pressure: obstruction (secretions, biting, kinks, coughing, pulmonary edema, pneumothorax).
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Low pressure/volume: disconnection, leak, tube displacement.
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Other alarms: low expired volume, apnea, high/low PEEP.
Initial Ventilator Settings (General Guidelines)
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Mode:
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AC (full support) or SIMV (partial support).
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Tidal Volume (VT): 5–10 mL/kg IBW (6–8 mL/kg preferred for lung protection).
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Rate (f): 10–20/min.
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FiO₂: 30–60% (100% if severe hypoxemia).
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Flow Rate: 40–60 L/min.
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I:E Ratio: 1:2 to 1:4.
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Sensitivity: –1 to –2 cmH₂O.
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PEEP: 4–6 cmH₂O.
Key Takeaways for Exams:
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Always use lowest FiO₂ possible to maintain O₂ sat.
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High PEEP → pneumothorax/barotrauma risk.
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Assess alarms before intervening.
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Modes: AC = full support, SIMV = weaning.
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Sensitivity too high/low → dyssynchrony.
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