1. Importance of Vascular Access
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Critically ill patients often require:
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IV medications (some cannot be given peripherally).
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Large volumes of fluids or blood.
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Special therapies (nutrition, dialysis, monitoring).
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In emergencies: dependable IV access is essential.
2. What is a Central Line?
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A catheter inserted into a large vein close to the heart (SVC or IVC).
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May be single lumen or multi-lumen.
Common Insertion Sites
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Internal Jugular (IJ) – most common; lowest complication rate.
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Subclavian – less common; higher risk for pneumothorax.
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Femoral – often emergent; highest infection risk, ideally removed within 24h.
3. Indications for Central Lines
a. Medications
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Irritant/vesicant drugs (e.g., potassium, vasopressors).
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Continuous vasoactive infusions.
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Multiple infusions at once.
b. Fluids
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Rapid, high-volume resuscitation or massive transfusion.
c. Nutrition
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TPN when enteral feeding not possible.
d. Other Uses
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Hemodialysis access (high flow).
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Poor peripheral access.
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Hemodynamic monitoring (CVP, Swan-Ganz).
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Device access (transvenous pacers, cardiac devices).
4. Types of Central Lines
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Standard central lines: single, double, triple lumen.
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More lumens = smaller size per lumen.
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PICC lines – inserted in arm, terminate in SVC.
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Tunneled lines – pass under skin; lower infection risk.
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Ports – implanted under skin, used for chemo.
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Hemodialysis lines – large lumens for high flow (200–300 mL/min).
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Introducers/MACs – large-bore, specialty access for resuscitation, pacing, devices.
5. Risks & Complications
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Bleeding – esp. with coagulopathies or insertion trauma.
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Pneumothorax/Hemothorax – esp. with subclavian approach.
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Arterial Cannulation – misplacement into carotid or femoral artery.
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Confirm with CXR or pressure transducer.
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Catheter Malposition – retrograde placement into IJ or head.
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Embolism – thrombus or air embolism (esp. during removal).
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Infection (CLABSI) – most common complication.
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Lowest risk: subclavian
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Moderate: IJ
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Highest: femoral
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6. Central Line Care
Patency & Flushing
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Flush once per shift with 10 mL NS using push-pause technique.
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Avoid flushing vasopressors → bolus effect.
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Never use 3 mL syringes (risk of catheter rupture).
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Occlusion: may require cathflo (tPA).
Infection Prevention
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Do not draw blood cultures from central line (prefer peripheral).
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Dressing:
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Occlusive, clean, dry, intact.
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Change q7 days or PRN; gauze → q24h.
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Sterile gloves, CHG prep, patient & staff masked.
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Use CHG-impregnated biopatch (blue side up, snug fit).
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Line Access
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Minimize manipulations.
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Scrub ports for 15 sec before access.
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Needleless caps, change q72–96h.
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Clamp line when not in use.
7. Insertion & Removal
Insertion
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Bedside sterile procedure.
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Full sterile barrier (gown, gloves, mask, drape, CHG prep).
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Ultrasound guidance preferred.
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Secure with StatLock or sutures.
Removal
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Greatest risk: air embolism.
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Patient flat.
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Valsalva maneuver (exhale forcefully).
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If vented → inspiratory hold.
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Steady pull, apply pressure ≥5 min.
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Occlusive transparent dressing afterward.
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If embolism suspected → place patient left lateral decubitus to trap air in RA.
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