Tuesday, September 23, 2025

AKI

Situation:

21 y.o. female, PMHx biliary colic s/p cholecystectomy. Presented with new-onset severe bilateral flank pain. Imaging showed bilateral kidney inflammation. Now with worsening AKI, hematuria, proteinuria, and coag-negative staph UTI.

Background:

  • PMHx: biliary colic s/p cholecystectomy

  • Initial workup: CT with bilateral renal inflammation

  • UTI: urine culture positive for coag-negative staph

  • Current Cr: 2.5 (plateaued)

  • Protein-to-creatinine ratio: elevated at 0.23

  • Labs: LDL, C3, C4 negative

  • US renal veins/arteries: no occlusion

  • Nephrology consulted

Assessment:

  • AKI – etiology unclear. Differential includes pyelonephritis vs AIN/ATI.

  • Possible pyelonephritis – on empiric ceftriaxone (Rocephin).

  • Pain – severe bilateral flank pain, managed with scheduled and PRN Dilaudid.

Recommendation/Plan:

  • Appreciate renal recs

  • f/u PR3, MPO, ANA, Anticardiolipin Abs

  • d/c IV fluids

  • Avoid NSAIDs and nephrotoxins

  • Trend BMP daily

  • Continue Rocephin 1g IV q24h

  • Continue Dilaudid 4mg PO q4h scheduled + 4mg PRN q4h

  • Continue Tylenol 1000mg q6h

  • Regular diet

  • Full Code

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